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Draw Those Molecules 2: Proteins '09

Anatomy & Physiology I, Trimester 1
 with Dr. Don DeWitt (v1 as of  9 / 21 / 09)
Go to A&P, Tri 1 Assignments  or  Go to A&P, Tri 1 Due Dates

Introduction:
The purpose of this series of homework assignments, is to direct your attention to the similarities and differences between the molecules of life.  With this year's change in the "in-class" structure there will be fewer opportunities for you to practice drawing molecules so the sometimes subtle differences will be more difficult to appreciate.  To address this learning-style problem, this homework requires that you take a pen or pencil and draw molecules!  You may NOT use a computer to draw the molecules but you should type your discussions (short ones!).  You may certainly use a computer to research the molecules of interest.  Of course, your class notes provided by the instructor should be sufficient. 

The Task:
Amino Acids:*





 a.

 What atoms are found in amino acids? How are they arranged? Are there any special groupings?
b.
 Why are some molecules water or lipid soluble? Can a molecule be water AND lipid soluble?
c. Which amino acids are hydrophilic?  Why?
d.
 Which amino acids are lipophilic? Why?
e.
 If a lipid soluble amino acid is dumped into a beaker of water, why does it dissolve?
f.
 What is the function of amino acids?
.
Oligopeptides:* a. How do you make a pentapeptide from five different amino acids?
b. How do you make three amino acids from Thyrotropin Releasing Hormone [GLU-HIS-PRO]?
.
Polypeptides:*
 a. How are proteins/polypeptides classified in terms of their inner organizations?  What level is absolutely needed before function can been obtained?  Why doesn't this hold for some proteins?
b. How are secondary and tertiary configurations of proteins held together?
c. How can the ends of polypeptides always be water soluble but the inner parts may be either water or lipid soluble?  What dictates this inner condition?
d. Describe five different functions of proteins.
* Note: Whether I ask for a graphic or ask for a discussion, ALL answers require graphic support.  In fact... I always look at your graphics first to get a sense of the likelihood of a perfect score on a question.
Formatting Rules:
General formatting rules may be found at:  http://users.bergen.org/dondew/bio/AnP/AnP1/AnPformat.html

Please create a typed document with hand-drawn graphics which can be placed in boxed areas on your document.  There is no page limit on this assignment but please do not draw huge molecules (e.g. a glucose larger than 2 inches is probably getting tooo big!)  Very tiny molecules are difficult to read too.

Due Dates and Course Value:
The due dates and percent value for this assignment may be found at the Due Dates website: Trimester 1

This document is:  http://users.bergen.org/dondew/bio/AnP/Anp1/AnP1Tri1/AnP1_Tri1_DTM2.html