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Vocabulary Checklist for Metabolism Unit Anatomy & Physiology I, Trimester 1, 2009 with Dr. Don DeWitt (v1 as of  3 / 3 / 09) This checklist is for you to use as we progress through our study of metabolism.  You will run into all of these terms as we progress.  If you group these terms into topics with which they are associated, you will be better organized and prepared for  PPAO2. –    Molecules of metabolism:         What is their structure and function?

+    acetylcoenzyme A (acetylCoA / CoA) *     +    acetaldehyde (found in the 2 steps           of ethanol fermentation -- Campbell pg 163)     +    adenosine di- (ADP) & triphosphate (ATP)     +    alpha-ketoglutarate *     +    carbon dioxide (CO2) *     +    citrate *     +    creatine and creatine phosphate (C/CP)     +    dihydroxyacetone phosphate (DHAP)     +    1,3-bisphosphoglycerate (1,3-DPG)     +    ethanol (ETH)     +    electrons     +    electron transport chain     +    flavin adenine dinucleotide (FAD / FADH2) *     +    fructose-1,6-bisphosphate (F1,6P)     +    fructose-6-phosphate (F6P)     +    fumarate *     +    glucose     +    glucose-6-phosphate (G6P) * found associated with the Krebs cycle and perhaps other places.     +    glyceraldehyde 3-phosphate (G3P)           [aka glyceraldehyde phosphate in Campbell on pg 154]     +    guanosine di- (GDP) and triphosphate (GTP) *     +    hydrogen ions (H+) *     +    isocitrate *     +    lactate / lactic acid (LAC)     +    malate *     +    nicotinamide dinucleotide (NAD+ / NADH) *     +    oxaloacetate *     +    oxygen (O2)     +    phosphate (Pi = when free in solution -> HPO42-) *           (-PO32- when added to another molecule           but abbreviated as a P inside a circle)     +    phosphoenolpyruvate (PEP)     +    3-phosphoglycerate (3-PG)     +    2-phosphoglycerate (2-PG)     +    pyruvate / pyruvic acid (PYR)     +    succinate *     +    succinyl coenzyme A (succinylCoA) *     +    water (H2O) * –    Pathways of metabolism:        What are their cellular or organismal locations, inputs, steps involved and outputs?     +    absorption     +    acetylCoA synthesis     +    aerobic catabolism     +    alcohol fermentation (yeah.. it is really 12 steps -- see pg 163)     +    anaerobic catabolism     +    ATP production and uses     +    beta-oxidation of fats     +    carbon dioxide production and use     +    chemiosmotic process     +    creatine phosphate production and use     +    citric acid cycle     +    deamination (-- see pg 164 Campbell)     +    digestion of carbohydrates, proteins,           lipids & nucleic acids     +    electron transport     +    excretion     +    FADH2 production and use     +    F0F1 complex operation (a.k.a., ATP synthase)     +    glycolysis     +    heat production     +    hydrolysis     +    Krebs cycle     +    lactic acid fermentation     +    NADH production and use     +    oxidative phosphorylation     +    oxygen production and use     +    pyruvate processing     +    urea production (-- see pg 874-5 Campbell) –    Can you think of the consequences of disruption of metabolic pathways caused by genetic mutations       that disable enzymes or environmental poisons that block certain metabolic steps?