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Physiological Control Systems 1
CURRICULUM
(Course Number:  Biology 112311)

Bergen County Academies
Hackensack, NJ 07601 (201) 343-6000

last update: 9 / 4 / 06


I. Course Description
VII. The core courses Biology and Advanced Biology at the Academy for the Advancement of Science and Technology (AAST) , and the Academy for Engineering and Design Technology (AEDT) comprise a two year investigation of some of the most critical biological topics in modern life. They are required of all AAST and AEDT students and are taken during the 10th and 12th grades. They do not comprise a comprehensive sequence. Rather, the two year effort explores a few topics in great depth. Those students who wish to gain a more comprehensive understanding of biology should select one or more biology electives such as Epidemiology, Genetics, Immunology, Molecular Biology 1-5, Botany, AP Biology, Biology Research, Physiological Control Systems 1 or 2, Virology, Zoology or others.

Physiological Control Systems1  (PCS) is an elective, one-trimester course available to any BCA student who has completed at least one year of Biology in good standing.  During the 2006-2007 school year, PCS will be offered during trimesters 1 and 3. 

This course is designed for those students who 1) plan to major in an area of biology in college; 2) wish to explore the topics of the the nervous, endocrine,  and cardiovascular systems at an advanced level equivalent to a college seminar course, or 3) are AEDT 11th grade students. PCS is a required core course for all 11th grade AEDT students.  PCS is not available to AMST students because they take Anatomy and Physiology during their junior year.

Because PCS is a core course for engineering students, its focus is to explore the physiology of humans from an engineer's point of view.


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II. PCS Course Goals

The focus of the PCS is an exploration of how the human body controls itself to maintain a stable internal environment with the special emphasis of an engineer's perspective. The course examines both physiological and nonliving (engineered) control systems that use negative feedback control systems. For instance we will compare control systems used by the human body and by engineers to maintain a human body’s or an oven’s temperature. 

The ultimate goal of the PCS will be to consider the technological challenges faced by NASA in the development of space vehicles such as the ones used in the ill-fated Apollo 13 moon mission that were used to carry three humans into outer space while maintaining their homeostatic mechanisms that use negative feedback control systems.

A negative feedback control system for a variable, such as temperature, requires: 
1) a sensor to detect the presence and condition of the sensed variable, 
2) a method of communicating (a.k.a. an afferent pathway) the status of the variable to a control center,
3) a control center (a.k.a. an integrating center) that accumulates sensor input and compares the status of the variable under control to a standard desired value known as a set-point,
4) a method of communicating (a.k.a. an efferent pathway) “decisions” from the integrating center out to mechanisms (a.k.a. effectors) that will change the status of the variable,
5) effectors which create a response which changes the system to oppose the direction of any changes in the variable (a.k.a. a stimulus).

As you may have surmised, a negative feedback control system is also known as a stimulus-response system in which the response is opposite the stimulus and the value of the variable is maintained within an acceptable range. In order to understand how engineers succeed with the challenges of human space flight, the circulatory, endocrine, nervous, renal and respiratory systems will be examined from the perspective of how they are used in control systems used in the human body to maintain homeostasis.  Homeostasis is the maintenance of a constant internal environment. 
 


The Engineering Viewpoint

An emphasis will be made to discuss the importance of understanding these biological control systems from an engineer's perspective when trying to design:
1)l micro-environments needed to maintain a human body in a hostile environment (e.g. a submarine, an airplane, a space ship, or even a space suit) or
2) replacement parts for the human body. 

In PCS we deal with the fundamental principles of basic physiology as a foundation for thinking about engineering challenges. 

Biophysics

Physics principles involving force, pressure, fluid flow, electron flow, electrical potentials, pressure gradients, resistance, viscosity, elasticity, etc. will be used to explain how:
 
1) the circulatory system works to move blood,
2) the endocrine system sends chemical messages,
3) the nervous system sends electrical and chemical messages,
4) the renal and respiratory systems are used in the management of blood gases and waste molecules.


Anatomy

Anatomical studies will be required as needed, but will NOT be a focus. In other words, students do not memorize all the names of the bones in the body, but are expected to know all the parts of the circulatory system because one can not discuss its function without knowing the names of its parts.



III. PCS Course Outline

The major topics of discussion are listed below. Details may be viewed in section IV: Student Objectives.
1) What is homeostasis?

2) The Human Nervous System

3) The Endocrine System

4) Why do you have a Circulatory System?

5) The paths of the respiratory gases

6) The Bulk Flow relationship


7) Cardiac Output

8) The measurement of blood pressure

IV. PCS Student Objectives

The objectives are listed in a separate document found at OBJECTIVES

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V. PCS Methodology
VII. The course is heavily focused on the necessarily detailed physiological and biophysical factual information about homeostasis involving the nervous, endocrine, circulatory and respiratory systems.  This focus is needed in order to analyze the problems associated with the construction of any engineered product or environment that interacts with living organisms. As a consequence, the format of classroom activities throughout the PCS course is lecture and discussion.  Assessment challenges are described below.
VI. PCS Assessment / Evaluation Procedures



In general assessments given in trimester 1 or 3 are the same, however on some occasions, scheduling conflicts force alternative plans, so please check the trimester 1 and trimester 3 assessment websites for specific details.  Assessments of the students include:
1) two take-home Questions For Your Consideration (QFYC)

a) Check the assessments website for specifics.
b) Check the assessments website for specifics. 


2) two in-class exams (a.k.a. PPAO) (25% each):
a) In-class Personal Performance Assessment Opportunity (PPAO #1):  This exam is presented as two styles: A) Combination of 15 multiple choice questions and B) two essay questions taken from a list of 4 provided at the beginning of the course. Part A will be given on one day dealing with the multiple choice questions. Part B will given on the following class dealing with the essays. (A: 30pts & B: 70pts)  
Click here for details: PPAO #1(Tri1)
or PPAO #1(Tri3)
b) In-class Personal Performance Assessment Opportunity (PPAO #2):  This exam is presented as two styles: A) Combination of 15 multiple choice questions and B) two essay questions taken from a list of 4 provided at the beginning of the course. Part A will be given on one day dealing with the multiple choice questions. Part B will given on the following class dealing with the essays. (A: 30pts & B: 70pts)  
Click here for details: PPAO #2(Tri1)
or PPAO #2(Tri3)

Due dates and values of each assignment are available at:
DUE DATES (Tri1)
or DUE DATES (Tri3)


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VII. Instructional Materials

This course covers six chapters in the textbook with extensive instructor written study notes and diagrams.
 
Textbook Chapters in Human Physiology: The Mechanisms of Body Function, 8th ed. by Vander, Sherman and Luciano, 2002

07 Homeostatic Mechanisms and Cellular Communication

08 Neural Control Mechanisms

09 The Sensory Systems

10 Principles of Hormonal Control Systems
Lecture Notes: 

A variety of instructor written notes are provided in the classroom, as well as instructor-written internet textbook chapters found at: http://users.bergen.org/dondew/bio/PCS/PCS1/PCS1.html#DeWitt Docs
Other Resources: 

Extensive internet offsite weblinks are available at: http://users.bergen.org/dondew/bio/PCS/PCS1/PCS1internet.html#internet. These are used throughout the course.